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Search Results to Timothy A McKinsey

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McKinsey, Timothy

One or more keywords matched the following items that are connected to McKinsey, Timothy

Item Type	Name
Academic Article	Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation.
Academic Article	Dose-dependent blockade to cardiomyocyte hypertrophy by histone deacetylase inhibitors.
Academic Article	Protein kinase D directly phosphorylates histone deacetylase 5 via a random sequential kinetic mechanism.
Academic Article	Protein kinase D-dependent phosphorylation and nuclear export of histone deacetylase 5 mediates vascular endothelial growth factor-induced gene expression and angiogenesis.
Academic Article	Isoform-selective HDAC inhibitors: closing in on translational medicine for the heart.
Academic Article	Targeting inflammation in heart failure with histone deacetylase inhibitors.
Academic Article	Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension.
Academic Article	Activation of the myocyte enhancer factor-2 transcription factor by calcium/calmodulin-dependent protein kinase-stimulated binding of 14-3-3 to histone deacetylase 5.
Academic Article	Therapeutic potential for HDAC inhibitors in the heart.
Academic Article	Selective class I histone deacetylase inhibition suppresses hypoxia-induced cardiopulmonary remodeling through an antiproliferative mechanism.
Academic Article	Signal-dependent repression of DUSP5 by class I HDACs controls nuclear ERK activity and cardiomyocyte hypertrophy.
Academic Article	Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5.
Academic Article	Toward transcriptional therapies for the failing heart: chemical screens to modulate genes.
Academic Article	Angiotensin II stimulates protein kinase D-dependent histone deacetylase 5 phosphorylation and nuclear export leading to vascular smooth muscle cell hypertrophy.
Academic Article	Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli.
Academic Article	Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4.
Academic Article	Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1.
Academic Article	A novel kinase inhibitor establishes a predominant role for protein kinase D as a cardiac class IIa histone deacetylase kinase.
Academic Article	Protein acetylation in the cardiorenal axis: the promise of histone deacetylase inhibitors.
Academic Article	Targeting histone deacetylases for heart failure.
Academic Article	?-Adrenergic receptor stimulation and activation of protein kinase A protect against a1-adrenergic-mediated phosphorylation of protein kinase D and histone deacetylase 5.
Academic Article	The biology and therapeutic implications of HDACs in the heart.
Academic Article	Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid.
Concept	Histone Deacetylase 1
Concept	Histone Deacetylase Inhibitors
Concept	Histone Deacetylase 2
Academic Article	Estrogen regulates histone deacetylases to prevent cardiac hypertrophy.
Academic Article	Class I HDACs regulate angiotensin II-dependent cardiac fibrosis via fibroblasts and circulating fibrocytes.
Academic Article	Targeting cardiac fibroblasts to treat fibrosis of the heart: focus on HDACs.
Academic Article	HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling.
Academic Article	Tubulin hyperacetylation is adaptive in cardiac proteotoxicity by promoting autophagy.
Academic Article	Class I HDAC inhibition stimulates cardiac protein SUMOylation through a post-translational mechanism.
Academic Article	Acetyl-lysine erasers and readers in the control of pulmonary hypertension and right ventricular hypertrophy.
Academic Article	Promiscuous actions of small molecule inhibitors of the protein kinase D-class IIa HDAC axis in striated muscle.
Academic Article	Novel Interaction of Class IIb Histone Deacetylase 6 (HDAC6) with Class IIa HDAC9 Controls Gonadotropin Releasing Hormone (GnRH) Neuronal Cell Survival and Movement.
Academic Article	Non-sirtuin histone deacetylases in the control of cardiac aging.
Academic Article	Myofibril growth during cardiac hypertrophy is regulated through dual phosphorylation and acetylation of the actin capping protein CapZ.
Academic Article	Histone deacetylation contributes to low extracellular superoxide dismutase expression in human idiopathic pulmonary arterial hypertension.
Academic Article	The potential of targeting epigenetic regulators for the treatment of fibrotic cardiac diseases.
Academic Article	Histone deacetylase 3 regulates the inflammatory gene expression programme of rheumatoid arthritis fibroblast-like synoviocytes.
Academic Article	Overlapping and Divergent Actions of Structurally Distinct Histone Deacetylase Inhibitors in Cardiac Fibroblasts.
Grant	Isoform-Selective HDAC Inhibitors for Age-Associated Diastolic Dysfunction
Academic Article	Histone deacetylase adaptation in single ventricle heart disease and a young animal model of right ventricular hypertrophy.
Academic Article	Class I HDACs control a JIP1-dependent pathway for kinesin-microtubule binding in cardiomyocytes.
Academic Article	Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism.
Concept	Histone Deacetylase 6
Academic Article	HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction.
Academic Article	Structural and in Vivo Characterization of Tubastatin A, a Widely Used Histone Deacetylase 6 Inhibitor.
Academic Article	Acute Kidney Injury Results in Long-Term Diastolic Dysfunction That Is Prevented by Histone Deacetylase Inhibition.
Academic Article	HDAC Inhibition Reverses Preexisting Diastolic Dysfunction and Blocks Covert Extracellular Matrix Remodeling.
Academic Article	Histone deacetylase 6 inhibition restores leptin sensitivity and reduces obesity.
Academic Article	HDAC6 modulates myofibril stiffness and diastolic function of the heart.
Academic Article	Histone Deacetylases: Molecular Mechanisms and Therapeutic Implications for Muscular Dystrophies.
Academic Article	HDAC11 inhibition triggers bimodal thermogenic pathways to circumvent adipocyte catecholamine resistance.

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Histone Deacetylase 2